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Isotretinoin, Proacne 10
Brand Names: Proacne 10, Accutane, Amnesteem, Claravis, Decutan, Isotane, Sotret, Oratane, Roaccutane, Isotrex, Isotrexin, Stiefel
Generic Name: Isotretinoin
Manufacturer: Various
While it has been claimed that Clomid "stimulates" production of LH and therefore of testosterone, in fact Clomid's activity is achieved not by stimulation of the hypothalamus and pituitary, but by blocking their inhibition by estrogen.
Clomifene acts by inhibiting the action of estrogen on the gonadotrope cells in the anterior pituitary gland. Since the estrogen receptors are prevented from recycling, the body perceives estrogen levels to be falsely lower than they actually are. As a result, the body releases more gonadotropin-releasing hormone from the hypothalamus, which drives the pituitary secretion of follicle-stimulating hormone (FSH), leading to a higher rate of ovulation and hence pregnancy.
Roaccutane
Brand Names: Roaccutane, Proacne 10, Accutane, Amnesteem, Claravis, Decutan, Isotane, Sotret, Oratane, Isotrex, Isotrexin, Stiefel
Generic Name: Isotretinoin
Manufacturer: Roche
Isotretinoin
Isotretinoin a drug derived from vitamin A used in the treatment of severe acne. It works by reducing the formation of sebum (natural skin oils) and keratin (a tough protein that is the major component of the outer layer of skin).
Side effects include itching, dryness and flaking of the skin, and cracking of the lips; depression may also be exacerbated. Isotretinoin may damage a developing fetus and therefore before starting treatment a woman is given a pregnancy test to ensure she is not pregnant. She should then avoid getting pregnant while taking the drug and for at least one month after stopping it.
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