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Mucosolvan PL / Mucosolvan Liquid
Brand Names: Mucosolvan and Mucoangin
Generic Name: Ambroxol Hydrochloride
See also generic Mucosolvan/Ambroxol here
Ambroxol is used for infections of the upper respiratory tract. It clears airways and eases cough.
Ambroxol is used for infections of the upper respiratory tract. It clears airways and eases cough. Preclinically, ambroxol, the active ingredient of MUCOSOLVAN, has been shown to increase respiratory tract secretion. It enhances pulmonary surfactant production and stimulates ciliary activity. These actions result in improved mucus flow and transport (mucociliary clearance). Improvement of mucociliary clearance has been shown in clinical pharmacologic studies. Enhancement of fluid secretion and mucociliary clearance facilitates expectoration and eases cough.
Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport.
Dosage and Administration
Adults : 1 prolonged action capsule once daily, either in the morning or evening after a meal
The capsules should not be opened or chewed, but swallowed whole with ample liquid. The "carrier tablets" which are occasionally present in the stools have released the active substance during their passage through the digestive system and are therefore without significance.
MUCOSOLVAN prolonged action capsules are not suitable for children under 12 years.
MUCOSOLVAN should not be used in patients known to be hypersensitive to ambroxol or other components of the formulation.
Pregnancy and Lactation
Preclinical studies as well as extensive clinical experience after the 28th week have shown no evidence of ill-effects during pregnancy. Nonetheless, the usual precautions regarding the use of drugs during pregnancy, especially during the first trimester, should be observed.
The drug enters breast milk, but is not likely to affect the infant when therapeutic doses are used.
MUCOSOLVAN is generally well tolerated. Mild upper gastro-intestinal side effects (primarily pyrosis, dyspepsia, and occasionally nausea, vomiting) have been reported, principally following parenteral administration. Allergic reactions have occurred rarely, primarily skin rashes. There have been extremely rare case reports of severe acute anaphylactic-type reactions but their relationship to ambroxol is uncertain. Some of these patients have also shown allergic reactions to other substances.
No symptoms of overdosage have been reported in man to date. If they occur, symptomatic treatment should be provided.
Administration of ambroxol together with antibiotics (amoxicilline, cefuroxime, erythromycin, doxycycline) leads to higher antibiotic concentration in the lung tissue.
No clinically relevant unfavorable interaction with other medications have been reported.
Prolonged action capsules 75 mg
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