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Climen 28

Brand Names: Climen 28
Generic Name:
Estradiol valerate + Cyproterone acetate
Manufacturer: Schering

Climen 28 is one form of oestrogen which is given to replace the oestrogen which the body is no longer producing.
Climen is indicated in patients (with intact uteri) suffering from climacteric symptomatology.
Climen therapy may be used as an adjunct in preventing osteoporosis in postmenopausal women.

16 white tabs each containing Estradiol valerate 2 mg,
12 pink tabs each containing Estradiol valerate 2 mg, cyproterone acetate 1 mg

Pregnancy, lactation, severe disturbances of liver function, jaundice or persistent itching during a previous pregnancy, previous or existing tumours of the liver, uterus, ovaries or breast or a suspicion of such tumours, endometriosis, existing or previous thromboembolic processes, severe diabetes mellitus with vascular changes, sickle-cell anaemia, disturbances of lipometabolism, a history of herpes of pregnancy, otosclerosis with deterioration during pregnancy.

Climen is not a hormonal oral contraceptive preparation.
Strict medical supervision is necessary in patients with diabetes, hypertension, varicose veins, a history of phlebitis, otosclerosis, multiple sclerosis, epilepsy, porphyria, tetany, chorea minor.
Reasons for immediate discontinuation of Climen
Occurrence for the first time of migrainous headaches or more frequent occurrence of unusually severe headaches, sudden perceptual disorders (eg disturbances of vision or hearing), first signs of thrombophlebitis or thromboembolic symptoms, a feeling of pain and tightness in the chest, pending operations (six weeks beforehand), immobilisation, onset of jaundice, onset of hepatitis, itching of the whole body, increase in epileptic seizures, significant rise in blood pressure, pregnancy.

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