online pharmacy and drugstore, cheap brand and generic drugs
Welcome Guest! Please login or create an account.
Home » Estrogen & Hormones » Tapazole

Pay with Bitcoin and get 25% discount! Click here.

There are no products to list in this category.

Buy Tapazole


Brand Names: Tapazole, Northyx
Generic Name:
Manufacturer: Various

Methimazole is used to treat an overactive thyroid gland (hyperthyroidism). Grave's disease is the most common cause of hyperthyroidism. It is an autoimmune disease resulting from antibodies that attach to receptors on thyroid hormone-producing cells in the thyroid gland and trigger overproduction of thyroid hormone. An enzyme (peroxidase) produces thyroid hormones, i.e., thyroxine (T4) and triiodothyronine (T3), by combining iodine with a protein called thyroglobulin. Methimazole prevents iodine and peroxidase from their normal interactions with thyroglobulin to form T4 and T3. This action decreases thyroid hormone production. Methimazole also interferes with the conversion of T4 to T3. Since T3 is more potent than T4, this also reduces the activity of thyroid hormones. The FDA approved methimazole in March 1999.

Tablet: 5 mg

Methimazole should be stored at room temperature, 15-30 C (59-86 F).

Methimazole is used for treating hyperthyroidism. It also is used for decreasing symptoms of hyperthyroidism in preparation for surgical removal of the thyroid gland or before inactivating the thyroid gland with radioactive iodine. Long-term use of methimazole may lead to a remission of the hyperthyroidism.

The initial adult dose of methimazole is:

  • 15 mg/day for mild hyperthyroidism,
  • 30-40 mg/day for moderately severe hyperthyroidism, and
  • 60 mg/day for severe hyperthyroidism.

The daily dose is divided into three doses administered every 8 hours. The maintenance dose is 5-15 mg/day. The usual initial children's dose is 0.4 mg/kg given in 3 divided doses administered 8 hours apart, and the maintenance dose is half the initial dose.

Warfarin (Coumadin) works by reducing the activity of vitamin K and therefore the formation of vitamin K dependent clotting factors. Methimazole may increase the activity of warfarin by further reducing the activity of vitamin K in the body.

There is evidence that methimazole may cause harm to the fetus during pregnancy.

Methimazole is excreted in breast milk and may potentially cause harm to the infant.

Methimazole is generally well-tolerated with side effects occurring in 3 out of every 100 patients. The most common side effects are related to the skin and include rash, itching, hives, abnormal hair loss, and skin pigmentation. Other common side effects are swelling, nausea, vomiting, heartburn, loss of taste, joint or muscle aches, numbness and headache.

Less common but more serious side effects include a decrease in white blood cells (agranulocytosis) and blood platelets (thrombocytopenia). Symptoms and signs of agranulocytosis include infections of the throat, the gastrointestinal tract, and skin with an overall feeling of illness and fever. Since platelets are important for the clotting of blood, thrombocytopenia may lead to problems with excessive bleeding. Hepatitis and death of liver cells (hepatic necrosis) have rarely been associated with methimazole.

News Update

September 7th, 2016:

October 26, 2015:
0 items

Hi, item recieved today. I am happy with your service, I have recieved prompt answers to my question...(read more)

Discrete Shipping
Prescriptions are discretely packed. Please make sure you have customs clearance on the products you order. If you are in doubt about customs please contact us BEFORE placing an order. If your order is not received after 28 days please let us know and we will investigate.
Safe and Secure
All transactions are 100% secure and fully confidential. This website is secured by a high-grade 256-bit SSL certificate that encrypts your information to ensure a safe and secure transaction.