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Brand Names: Lyndinette, Estinyl, Meliane
Generic name: Gestodene+Ethinyl estradiol
Manufacturer: Gedeon Richter
Each tablet contains:
Lindynette 20 tab Gestodene 0.075 mg, ethinyl estradiol 0.02 mg
Lindynette 30 tab Gestodene 0.075 mg, ethinyl estradiol 0.03 mg,
Therapeutic actions: Ethinylestradiol is a is a form of estrogen that is involved in the development and maintenance of the female reproductive system.
Indications: Estrogens are prescribed for several reasons:
- To provide additional hormone when the body does not produce enough of its own, such as during menopause. They can also help to relieve a genital skin condition called vaginal or vulvar atrophy.
- To help prevent weakening of bones (osteoporosis) in women past menopause.
Contraindications and cautions: Before taking Ethinylestradiol:
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will need to make. For estrogens and progestins, the following should be considered:
allergies - Tell your doctor if you have ever had any unusual or allergic reaction to estrogens or progestins. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy - Estrogens and progestins are not recommended for use during pregnancy or right after giving birth. Becoming pregnant or maintaining a pregnancy is not likely to occur around the time of menopause.
Breast-feeding - Estrogens and progestins pass into the breast milk and can change the content or lower the amount of breast milk. Use of this medicine is not recommended in nursing mothers.
Older adults - Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of estrogens and progestins in the elderly with use in other age groups.
Checking-up visits - It is very important that your doctor check your progress at regular visits to make sure this medicine does not cause unwanted effects. These visits will usually be every year, but some doctors require them more often.
Additionally, it is not yet known whether the use of estrogens increases the risk of breast cancer in women. Therefore, it is very important that you regularly check your breasts for any unusual lumps or discharge, and report any problems to your doctor. You should also have a mammogram (x-ray pictures of the breasts) done if your doctor recommends it. Because breast cancer has occurred in men taking estrogens, regular breast self-exams and exams by your doctor for any unusual lumps or discharge should be done.
Other medical problems - The presence of other medical problems may affect the use of estrogens and progestins. Make sure you tell your doctor if you have any other medical problems, especially:
Calcium, too much or too little in blood
Diabetes mellitus (sugar diabetes)
Liver tumors, benign
Lupus erythematosus, systemic
Porphyria - Estrogens may worsen these conditions.
Blood clotting problems, or history of during previous estrogen therapy. (Estrogens are usually not used until blood clotting problems stop. Using estrogens is not a problem for most patients without a history of blood clotting problems due to estrogen use.)
Cancer of the uterus
Fibroid tumors of the uterus - Estrogens may interfere with the treatment of breast or bone cancer or worsen cancer of the uterus when these conditions are present.
Changes in genital or vaginal bleeding of unknown causes - Use of estrogens may delay diagnosis or worsen condition. The reason for the bleeding should be determined before estrogens are used.
Gallbladder disease or gallstones (or history of)
High Cholesterol or triglycerides (or history of)
Pancreatitis (inflammation of pancreas) - Estrogens may worsen these conditions. While estrogens can improve blood cholesterol, they may worsen blood triglycerides for some people.
Hypothyroid (too little thyroid hormone) - Dose of thyroid medicine may need to be increased.
Vision changes, sudden onset including bulging eyes or double vision, migraine headache, vision loss, partial or complete - Estrogens may cause these problems.
Adverse effects: Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Check with your doctor as soon as possible if any of the following side effects occur:
Breast pain or tenderness, dizziness or light-headedness, headache, swelling of feet and lower legs, rapid weight gain, or vaginal bleeding, bloating or gas, flu-like symptoms, mental depression, muscle aches, nausea (taking tablet with food may decrease this symptom).
Breast lumps, change in vaginal discharge, discharge from nipple, nausea and vomiting, pains in stomach, side, or abdomen, pain or feeling of pressure in pelvis, yellow eyes or skin, severe or sudden headache, sudden loss of coordination, pains in chest, groin, or leg (especially calf), sudden and unexplained shortness of breath, sudden slurred speech, sudden vision changes, or weakness or numbness in arm or leg.
The side effects listed above may not include all of the side effects reported by the drug’s manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking estrogens and progestins, it is especially important that your health care professional know if you are taking any of the following: Cyclosporine (e.g., Sandimmune�) - Estrogens can prevent cyclosporine’s removal from the body which can lead to kidney or liver problems caused by too much cyclosporine.