online pharmacy and drugstore, cheap brand and generic drugs
Welcome Guest! Please login or create an account.

Home » Blood and heart » Cascor XL

Pay with Bitcoin and get 25% discount! Click here.

There are no products to list in this category.
Buy Cascor, Cardizem

Cascor XL

Brand name: Cascor XL, Cardizem, Dilacor, Tiazac
Generic name: Diltiazem HCl
Manufacturer: Ranbaxxy

Diltiazem is a drug that is used for treating heart pain (angina), high blood pressure, and abnormal heart rhythms. It belongs to a class of drugs called calcium channel blockers (CCBs), which includes amlodipine (Norvasc), verapamil (Calan, Isoptin), nifedipine (Adalat, Procardia) as well as others. CCBs block the entry of calcium into muscle cells that make up the heart and that surround the arteries. It is the entry of calcium into these cells that causes the cells to contract, allowing the heart to pump blood, and the arteries to narrow. By blocking the entry of calcium, diltiazem decreases the force of contraction of the heart and its rate of contraction. It also relaxes the muscles surrounding the arteries, allowing the arteries to widen (dilate). In order to pump blood, the heart needs oxygen. The harder the heart works, the more oxygen it requires. Angina occurs when the supply of oxygen to the heart is inadequate for the amount of work the heart must do. By dilating arteries, diltiazem reduces the pressure in the arteries into which the heart must pump blood, and, as a result, the heart needs to work less and requires less oxygen. By reducing the heart's need for oxygen, diltiazem relieves or prevents angina. Dilation of the arteries also reduces blood pressure. The FDA approved diltiazem in 1982.

Tablets (immediate release): 30, 60, 90, and 120 mg. Tablets (extended release): 120, 180, 240, 300, 360, 420 mg. Capsules (extended release): 60, 90, 120, 180, 240, 300, 360, 420 mg. Injection: 5 mg/ml. Powder for injection: 25 mg.

Tablets, capsules and powder for injection should be stored at room temperature, 15-30 C (59-86 F). Solution for injection should be stored at 2-8 C (36-46 F).

Diltiazem is used for treating heart pain (angina), high blood pressure, and abnormal heart rhythms such as atrial fibrillation, atrial flutter and paroxysmal supraventricular tachycardia.

Adult oral doses range between 120 and 480 mg daily. Immediate release tablets are administered up to 4 times a day. Extended release formulations are administered once daily at approximately the same time each day and should not be crushed or chewed.

Administration of diltiazem with digoxin (Lanoxin) can increase digoxin blood levels. Therefore, blood levels of digoxin usually are monitored to avoid toxicity from digoxin. Similarly, concurrent administration of diltiazem with an anti-seizure medication, carbamazepine (Tegretol), can increase blood levels of the seizure medication, and occasionally lead to toxicity. Diltiazem increases blood levels of lovastatin (Mevacor), atorvastatin (Lipitor) and simvastatin (Zocor), possibly increasing the risk of adverse effects. Diltiazem may increase blood levels of buspirone (Buspar), midazolam (Versed), triazolam (Halcion) and diazepam (Valium) by reducing their breakdown and elimination from the body by the liver. This can lead to toxicity from these drugs. Rifampin (Rifamate, Rifadin, Rimactane) reduces the effect of diltiazem by reducing its levels in blood to undetectable levels.

There are no adequate studies of diltiazem in pregnant women.

Diltiazem is excreted in breast-milk. To avoid adverse effects in the infant, diltiazem should not be taken while nursing.

Side effects include constipation, nausea, headache, rash, edema (swelling of the legs with fluid), low blood pressure, drowsiness, and dizziness. Liver dysfunction and overgrowth of the gums also may occur. Diltiazem can cause mildly abnormal liver tests that usually return to normal with discontinuation of the medication. When diltiazem is given to individuals with heart failure, symptoms of heart failure may worsen because these drugs reduce the ability of the heart to pump blood. Like other drugs for high blood pressure, diltiazem is associated with sexual dysfunction.

News Update

September 7th, 2016:

October 26, 2015:
0 items

EMS order arrived in 5 days. Products in perfect condition....(read more)

Discrete Shipping
Prescriptions are discretely packed. Please make sure you have customs clearance on the products you order. If you are in doubt about customs please contact us BEFORE placing an order. If your order is not received after 28 days please let us know and we will investigate.
Safe and Secure
All transactions are 100% secure and fully confidential. This website is secured by a high-grade 256-bit SSL certificate that encrypts your information to ensure a safe and secure transaction.