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Brand Name: Telfast, Allegra
Generic Name: Fexofenadine hydrochloride
Fexofenadine hydrochloride (brand names include Allegra and Telfast) is an antihistamine drug used in the treatment of hayfever and similar allergy symptoms.
Fexofenadine hydrochloride, the active ingredient of TELFAST, is a histamine H1- receptor. It has the following chemical structure.
The molecular weight is 538.13 and the empirical formula is C32H39NO4HCI.
Fexofenadine hydrochloride is a white to off-white crystalline powder. It is freely soluble in methanol and ethanol, slightly soluble in chloroform and water, and insoluble in hexane Fexofenadine hydrochloride is a racemate and exists as a zwitterion in aqueous media at
TELFAST is formulated as a tablet for oral administration. Each tablet contains 30 mg or 60 mg fexofenadine hydrochloride (depending on the dosage strength) and the following excipients: croscarmellose sodium, magnesium stearate, microcrystalline cellulose, and pregelatinized starch. The aqueous tablet film coating is made from hydroxypropyl methylcellulose, iron oxide blends, polyethylene glycol, povidone, silicone dioxide, and titanium dioxide.
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