MTP Kit (Abortion Kit) – US Domestic


MTP Kit (Mifepristone & Misoprostol) Type Abortions are a complete abortion kit that can be used for early abortions in women. This abortion kit contains two drugs, Mifeprex and Misoprostol, prescribed to women less than nine weeks pregnant. It comes in a combination pack containing one tablet of Mifeprex 200 mg and four tablets of misoprostol 200 mcgs. It is a medication abortion that requires taking pills orally. These pills are given by the doctor when you go to the clinic. It works by blocking progesterone and increasing uterine contraction to cause an abortion. Abortion takes place within 3-4 days after conception. Follow up with your doctor after two weeks.

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MTP Abortion Kit

How It Works

MTP Kit works to block the effects of progesterone which causes the placenta to detach from the uterus. It helps soften the cervix and increases uterine contractions so that the uterus can empty itself. When the uterus begins to bleed, it usually contains blood clots that are then passed out through the vagina.

A woman who’s seven weeks pregnant has a receptacle that looks like a thin grain. A woman who’s 9 weeks pregnant has a receptacle that looks like a kidney bean shape. You should get an ultrasound done after two weeks to see if the abortion has been completed.


MTP Kit is used for the following purposes:

How to use mifepristone oral

Mifepristone Oral is used to terminate the pregnancy. This drug works best when it is taken early in the pregnancy. You must take mifepristone orally every day for up to 10 days. Your doctor will tell you when to begin taking mifepristone and how long you should continue treatment.

Before you begin using mifepristONE, read the information provided by your doctor about possible side effects. Also, keep the written information given to you by your doctor.

If you miss a dose of mifepristone, skip the missed dose and take your next scheduled dose. Do NOT take 2 doses at once. Continue to take mifepristone’s for the full length of your prescribed treatment period.

Do not stop taking mifepristone unless told to do so by your doctor. Stopping treatment too soon could make the problem worse and cause complications.

Tell your doctor if you are pregnant or plan to become pregnant while taking mifepristone. Women who are pregnant or think they might be pregnant should avoid becoming pregnant during treatment. They should talk to their doctors immediately if they experience symptoms such as vaginal bleeding or spotting, pain or tenderness in the lower abdomen, breast lumps, nausea, vomiting, diarrhea, dizziness, headache, fever, chills, unusual tiredness or weakness, shortness of breath, sore throat, cough, difficulty breathing, swelling of the hands or feet, rash, itching, changes in vision, confusion, seizures, or fainting.

You should not drink alcohol while you are taking mifepristone.



  • Abortion – MTP kit is used for terminating pregnancies up to nine weeks.



MTP Kit consists of 1 tablet of mifepristone and four tablets of misoprostol. Mifepristone is intended to be taken by mouth with water. You should take the four tablets of misoprostol within the next 72 hours after taking them. Your doctor will tell you when you should take it (or not).

You can take misoprostol either orally or vaginally. To administer buccal tablets, you need to place them in your cheek pouch. Do not swallow them immediately. Put two pills of misoprostol on one cheek and the other two pills on the other cheek (in your cheek pouch behind your teeth). Wait until the contents dissolve. After taking the pills for 25-30 minutes, drink some water. Bleeding usually begins within the first four hours. You should keep a few sanitary pads nearby as the bleeding will be heavy than usual.

For vaginal administration, it is best to lie down and insert the four tablets into your vagina. If the pills fall off before the bleeding starts, reinsert them. If the pills fall off before the bleeding starts, do worry as they may be causing harm to the baby.

After two weeks, visit your doctor to confirm whether abortion has taken place or not. In order to avoid severe cramping and painful abdominal pain, your doctor may advise you to take a tablet containing Ibuprofen one hour before the administration of misoprostol.

Missed Dose: This medication is taken as prescribed by your doctor. Therefore, the chances that you’ll miss a dose are not possible

Overdose: This medication is usually taken in the company of a doctor. However, if your doctor advises you to take these tablets at home and overdosage is suspected, contact your GP immediately.

Important Notice

You should inform your doctor before taking MTP Kit.


  • You should not take Mifepristone if you are allergic to it.
  • If you have a blood clotting disorder.
  • If you have a chronic illness, such as a kidney or liver disease, you may need to take
  • If you suffer from any type of disease, you need to take care of yourself.
  • If you have high blood pressure.
  • If you have a past history of heart attacks, strokes, etc.
  • If you have severe iron deficiency.
  • If you have any hereditary skin diseases.


Side Effects

Side effects of MTP Kit may include:


  • Headaches
  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Chills or hot flushes
  • Fatigue
  • Shivering
  • Pelvic pain
  • Dyspepsia
  • Heavy menstrual bleeding


If you soak two sanitary napkins or more within two hours, or if you experience any side effects for longer than two hours, contact your doctor immediately

Effects on Ability to Drive and Use Machines

No studies on the effects of driving and operating machinery have been conducted. However, there are several reports of women experiencing nausea, vomiting, and diarrhea while taking mifepristone and/or misoprostol. Women should take caution when driving or operating heavy equipment immediately following treatment. When possible, it is recommended that patients wait one week following mifepristone administration before attempting to drive or operate heavy machinery.

Materials and Methods

This study was conducted retrospectively in Sri Manakula Vinyagar Medical college and hospital during the period of July 2013 -June 2014. A total of 50 patients admitted with the diagnosis of incomplete abortion were included in the study. Data were collected from case sheets containing information about the demographic profile, clinical presentation, investigations, and management. Statistical analysis was done using SPSS version 16.0.


Out of fifty cases of incomplete abortions, the majority (34%) were in the age group 20 – 29 years followed by 30% in the age group 30 – 39 years. The majority (44%) of the patients belonged to the lower middle class while 38% were upper middle class. The most common cause of abortion was found to be rape (32%), followed by contraceptive failure (28%). The majority (64%) of the patients reported within 3 days of pill consumption. Duration of gestation ranged from 2 weeks to 8 months. Amongst those who did not report any complication, most (62%) underwent surgical evacuation. In those who presented with signs of infection like fever, pain abdomen, etc., the majority (80%) received antibiotics and (60%) required a blood transfusion. The majority (76%) of the patients were managed conservatively. Out of 34 patients who bled profusely, the majority (84%) were treated surgically. Out of 10 patients who were hemodynamically stable, the majority (70%) were managed medically.


Incomplete abortion is still one of the leading causes of maternal morbidity and mortality worldwide. There are many factors responsible for incomplete abortion such as socio-economic conditions, lack of awareness regarding emergency obstetric care, poor quality of health services, delay in seeking help, and misdiagnosis. Abortion pills are easily accessible over-counter drugs and hence there is a greater risk of misuse. As per our observation, the majority of the patients did not seek medical advice till it was too late. Hence, proper counseling and education regarding the safe use of abortifacient drugs are essential.


Therapeutic Indication

Mifepristone/misoprostol (MTP Kit) is indicated for the medical abortion of pregnancies of 60 days or less gestational age. This product is used together with misoprostol. Mifeprex® is manufactured by Merck & Co., Inc.

The drug is available in oral tablets, sublingual tablets, vaginal suppositories, and injectable solutions. The oral tablet and sublingual tablet are taken orally once daily starting 24 hours prior to mifepristone administration and continuing for 5 consecutive days. A vaginal suppository should be inserted into the vagina 12 hours prior to mifepristone administration and remain there for 4 consecutive days. The injectable solution must be administered intramuscularly within 15 minutes prior to mifepristone administration and repeated 48 hours later.

Drug Interactions

Some drugs may interfere with MTP Kit and cause it not to work properly. Let your doctor know if you’re taking any herbal, OTC (over-the-counter), recreational, or any other drug.


  • Antibiotics such as erythromycin
  • Antifungals such as ketoconazole
  • Corticosteroids such as dexamethasone
  • Alprazolam
  • Amlodipine
  • Carbamazepine
  • Chlorpheniramine
  • Atorvastatin
  • Cyclosporine
  • HIV Protease inhibitors such as indinavir and ritonavir
  • Phenytoin
  • Rifampin


Interaction with alcohol

Alcohol can increase the risks of experiencing side effects, but it won’t necessarily cause them. Do not consume alcohol while taking this medication.

Storage Instructions

MTP Kit should always be stored properly and safely.

  • You should keep the medicine away from direct exposure to heat, moisture, and light.
  • Keep the medicine away from children.
  • Once the pack is open, store the remaining pills inside an airtight container.
  • Do not take the medication past its expiration date.



What is an MTP kit for abortion?

MTP Kit is an abortifacient drug combination that comes in the form of a combi pack containing one tablet of Mifeprex 200 mg and four tablets of Misoprostol 200 mcg. It is used to induce abortions in women who are no longer than nine weeks (63 days) pregnant.

Can I use the MTP Kit safely?

MTP Kit is an effective medication that is used for the abortion of pregnancy in women. It has been clinically proven to terminate an intrauterine pregnancy of 63 days gestation period. Millions of women worldwide use it for over 20 years. It doesn’t affect someone’s ability to conceive when he or she is ready.

How effective is the MTP Kit?

MTP Kit is an extremely effective method of abortion with a success rate of 93-98% Pregnant women who are in their first month of pregnancy can use this kit to terminate their pregnancies.

How long does it take for MTP Kit to work?

In most cases, the pregnancy tissues are expelled out within the first 4-6 hours. Cramping and bleeding slow down after the expulsion of the pregnancy tissues. Cramping stays on for a period of 24-48 hours. The whole abortion process gets completed within 3-4 days. You should follow up with your doctor after two weeks.

How do I take the doses of MMP Kit?

For administering Mifeprex (Mifepristone), you are intended to take one 200mg tablet first. After taking this pill you can go back to your regular routine and continue with it. The next step is taking four tablets of misoprostol 200 mcg either orally or vaginally as you prefer. These are taken within 72 hours. However, after taking mifepristone, wait for 24 hours and take the four tablets of misoprostol afterward. You may experience bleeding that lasts for up to 8 hours (or even 12 hours in some instances). You should rest for 24 hours as you’ll be feeling nauseous. If you experience any discomfort or pain during the process, you may take pain medication and anti-nauseous medications before taking Misoprostol.

Are there any side effects of MTP Kit?

Common side effects of MTP Kit include headache, nausea, vomiting, diarrhea, fatigue, and dizziness. If you experience any symptoms for more than 24 hours or if they persist, seek medical help immediately

These pills should not be taken when they’re not needed.

While the abortion pill may be a safe option for the early termination of pregnancy, it usually isn’t right for everyone. Therefore, you shouldn’t take MTP Kit if any of these things apply to you:


  • An ectopic pregnancy is a pregnancy that has been implanted outside the uterus. It can only be treated by medical professionals.
  • Chronic adrenal or hepatic failure.
  • If you have HIV, the pregnancy termination process can put you at an increased risk of contracting HIV. Therefore, you should take antibiotics at the same time as using the abortion pill and see your doctor before doing so.
  • If you have an STI, you should go to the doctor for treatment.
  • You should have an intrauterine device (IUD) removed before taking the abortion pills.
  • Porphyria is an inherited disease such as porphyrins is that affects the blood’s ability to carry oxygen to organs and tissue.


How can you confirm an abortion?

You should schedule a follow-up appointment to make sure that the procedure has been completed. You can visit your nearby clinic where a medical professional will perform an examination, blood test, ultrasound, or any other procedure.

After an abortion, there are some important things you need to be aware of.

Plan to take some time off from work for a few days after the abortion. After an abortion, there are certain precautions that you must take.


  • Don’t exercise too hard for the first week.
  • Avoid inserting anything into your vagina for two to three weeks.
  • Don’t stimulate your nipples to reduce breast discharge (mastitis).


Most symptoms usually go back to normal after 24 hours. Plan to take it easy and let your body be your guide.

What might happen if I take this medicine?

It’s common to worry if something’s going to be okay. There’s nothing to worry about. However, there are certain things you need to watch out for after your abortion procedure.

Complications may include:


  • A fever above 101 degrees for more than 24 hours.
  • Bleeding that doesn’t stop – soaking two or more pads in one hour for two hours in a row.
  • If nausea, vomiting, or diarrhea last for more than 24 hours, seek medical attention immediately.
  • Vaginal discharge that smells bad.
  • Severe pain or discomfort that doesn’t go away even after taking medication.
  • Continued symptoms of pregnancy for at least two to four weeks.


If you experience any of these things, contact your doctor immediately. These signs may indicate that additional treatment is required.

Do they differ from each other?

The abortion pill is sold under different names, including Mifepristone (RU486), Medical abortion, medication abortion, or medicated abortion are the exact same thing as an abortion pill.





Additional information

How many?

1Kit, 2 Kit, 3 Kit


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